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BRCA-1 and BRCA-2
(Breast Cancer Gene 1 and 2) Tests

The Test Sample
 
What is being tested?
BRCA-1 and BRCA-2 are two genes that are linked with hereditary breast and ovarian cancers. An estimated 10% to 15% of all cases of breast cancers are inherited. About 5% are due to mutations in the BRCA-1 gene and about 5% are due to mutations in the BRCA-2 gene. Only BRCA-2 mutations have been linked to risk of male breast cancer.

How is the sample collected for testing?
The test for BCRA mutations is done on a blood sample collected by needle from a vein in the arm. The test does not require surgical biopsy of breast or ovarian tissue.


This page was last modified on April 29, 2004.
 

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