Total Protein Test
Also known as: TP
Related tests: Albumin; Liver function tests
The Test
How is it used?
Total protein measurements can tell your doctor about whether you are malnourished and about kidney disease, liver disease, and many other conditions. If total protein levels are abnormal, further tests must be done to find which particular protein is abnormal, so that a diagnosis can be made.
When is it requested?
Total protein may be measured along with several other tests to help diagnosis of a disease if you have symptoms that suggest a liver or kidney disorder, or have fluid collecting in your tissues (oedema).
What does the test result mean?
Low total protein levels can suggest a liver disorder, a kidney disorder, or a disorder in which protein is not digested or absorbed properly. More specific tests, such as albumin and liver enzyme tests, must be performed to make an accurate diagnosis. High total protein levels can indicate dehydration or some types of cancer that lead to an accumulation of an abnormal protein (such as multiple myeloma).
Is there anything else I should know?
Prolonged application of a tourniquet during blood collection can increase total protein levels. Drugs that may increase protein levels include anabolic steroids, androgens, growth hormone, insulin, and progesterone. Drugs that may decrease protein levels include oestrogens.
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