Cushing's syndrome

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Symptoms of Cushing's syndrome

The signs and symptoms that occur with Cushing’s syndrome depend on a number of factors that include the cause of the Cushing’s syndrome, the level of cortisol or ACTH, the age and sex of the patient.

They include obesity around the waist and also fat laid down across the shoulders and neck; arms and legs tend to be thin in relation to the body.  The face may be round and flushed and bruising is commonly present especially on the legs; wounds may heal very slowly.  There may be muscle weakness, tiredness, ‘stretch’ marks around the stomach, hips and thighs, pigmentation of the skin, particularly of scars and inside the mouth, raised blood pressure (hypertension), too much blood sugar (diabetes), fragile bones (osteoporosis).  Women usually have menstrual irregularities. Men may suffer with impotence.

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