Lymphoma
Comparison Table
The following table illustrates the two most commonly used classifications plus an older classification. Because of differences in how the lymphomas are described, there is not a one-to-one comparison between the systems, and a single disease could be known by multiple names.
Comparison of Some Non-Hodgkin Lymphoma Classifications
Note: These classifications cannot always be compared
Comparison of Some Non-Hodgkin Lymphoma Classifications
| NCI* (Working Formulation) (Older Classification) | REAL** | WHO*** Classification |
|---|---|---|
| B cell lineage/NHL | Mature B cell lymphoma | |
| Low grade lymphoma Small lymphocytic lymphoma (plasmacytoid) Follicular lymphoma (small cleaved cell, large cell, mixed cell) High Grade lymphoma Diffuse lymphoma (small cleaved, large, mixed cell) Diffuse immunoloblastic lymphoma Burkitt Lymphoma Burkitt-like Lymphoma Lymphoblastic lymphoma |
B-cell chronic lymphocytic leukaemia Lymphoplasmacytic lymphoma Nodal and extranodal marginal B-cell lymphoma Follicular Center, grades I, II, and III lymphoma Mantle Cell lymphoma |
B cell CLL / SLL Splenic marginal zone B-cell lymphoma Extranodal marginal B cell lymphoma Follicular lymphoma Mantle cell lymphoma Diffuse large B-cell lymphoma Burkitt’s lymphoma |
| T and NK Cell Neoplasms | T and NK Cell Neoplasms | |
| Mature T cell lymphoma | ||
| Small lymphocyte lymphoma Mycosis Fungoides Diffuse lymphoma (small cleaved, large, mixed cell) Large cell immunoblastic lymphoma |
Adult T cell lymphoma Mycosis fungoides Anaplastic large cell lymphoma not otherwise characterised Immunoblastic T cell lymphoma |
|
| Langerhans cell histiocytosis Langerhans cell sarcoma Interdigitating dendritic cell sarcoma/tumour Follicular dendritic cell sarcoma/tumour Dendritic cell sarcoma, not otherwise specified |
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| * NCI = National Cancer Institute ** REAL = Revised European American Lymphoma *** WHO = World Health Organisation |
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