What is it?Pancreatic insufficiency is the inability of the
pancreas to produce and/or transport enough digestive enzymes to break down food in the intestine and allow its absorption. It typically occurs as a result of long term pancreatic damage -- damage that may be caused by a variety of conditions. It is most frequently associated with
cystic fibrosis in children and with chronic
pancreatitis in adults; it is less frequently but sometimes associated with
pancreatic cancer.
Pancreatic insufficiency usually presents with symptoms of malabsorption, malnutrition, vitamin deficiencies, and weight loss (or inability to gain weight in children) and is often associated with steatorrhoea (pale, fatty, foul-smelling, floating stools). Diabetes may also be present in adults with pancreatic insufficiency.