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Sjögren's Syndrome


Tests
Tests for Sjögren’s syndrome may include:

  • Positive Schirmer’s test. In this test, a piece of filter paper is hooked over the lower eyelid and left there for 5 minutes. It is used to assess dryness of the eyes, though is not specific for Sjogren’s.  Rose Bengal staining of the eyes can be used to look for scarring.
  • Antinuclear antibodies (ANA) (positive) 
  • Rheumatoid factor (RF) (often positive)
  • Antibodies specific to Sjögren’s syndrome (SS): anti-SS-A and SS-B; SS-A is also called Ro, while SS-B is also called La (usually positive)
  • Salivary gland antibodies
Other tests:
  • In uncertain cases, salivary gland biopsy  

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